Name: transforming growth factor-beta in cancer therapy, volume ii: cancer treatment and therapy (en Inglés)
SKU: 25445453
Price: 5467.91 MXN
Availability: InStock
Author: Heldin, C. -H ; Jakowlew, Sonia B.
ISBN: 9781617377365

portada transforming growth factor-beta in cancer therapy, volume ii: cancer treatment and therapy (en Inglés)

transforming growth factor-beta in cancer therapy, volume ii: cancer treatment and therapy (en Inglés)

Formato

Libro Físico

Prefacio de

C. -H Heldin

Ilustrado por

Sonia B. Jakowlew

Editorial

Humana

Autor

Heldin, C. -H ; Jakowlew, Sonia B.

Año

2010

Idioma

Inglés

N° páginas

786

Encuadernación

Tapa Blanda

Dimensiones

25.4x17.8x4.1 cm

Peso

1.38 kg.

ISBN

1617377368

ISBN13

9781617377365

Categorías

Oncología
Farmacología
Biología celular (citología)

transforming growth factor-beta in cancer therapy, volume ii: cancer treatment and therapy (en Inglés)

C. -H Heldin (Prefacio de) · Sonia B. Jakowlew (Ilustrado por) · Humana · Tapa Blanda

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Reseña del libro "transforming growth factor-beta in cancer therapy, volume ii: cancer treatment and therapy (en Inglés)"

Transforming Growth Factor-B in Cancer Therapy, Volume II: Cancer Treatment and Therapy The chapters in this volume confer an abundance of knowledge about the current state ofour understanding oftransforming growth factor-B (TGF-B) in cancer treatment and therapy. Unlike several more traditional positive polypeptide growth factors that stim- ulate cellular proliferation, the prototypical TGF-B is now known to inhibit the growth of most normal cell types, including those of epithelial and mesenchymal origin. However, there are examplesofcell types that can be stimulated by TGF-B under certain conditions. TGF-B also induces the accumulation of matrix molecules by stimulating their synthesis as well as inhibiting their degradation. Moreover, TGF-B induces apoptosis of certain cell types, thereby restricting their proliferation. OveractivityofTGF- has been linked to several diseases. For instance, the effect ofTGF- on matrix accumulation contributes to fibrotic conditions, like glomerulonephritis, lung fibrosis and liver cirrhosis (1). TGF- has a very complicated role in cancer that is only beginning to be understood.