Name: synthetic aspects of aminodeoxy sugars of antibiotics (en Inglés)
SKU: 24700743
Price: 2205.71 MXN
Availability: InStock
Author: Pelyvas, Istvan F. ; Monneret, Claude ; Herczegh, Pal
ISBN: 9783642734014

portada synthetic aspects of aminodeoxy sugars of antibiotics (en Inglés)

synthetic aspects of aminodeoxy sugars of antibiotics (en Inglés)

Formato

Libro Físico

Autor

Editorial

Año

2011

Idioma

Inglés

N° páginas

244

Encuadernación

Tapa Blanda

Dimensiones

24.4x17x1.4 cm

Peso

0.43 kg.

ISBN

3642734014

ISBN13

9783642734014

Categorías

Medicina preclínica: ciencias básicas
Farmacología
Bioquímica

synthetic aspects of aminodeoxy sugars of antibiotics (en Inglés)

Istvan F. Pelyvas (Autor) · Claude Monneret (Autor) · Pal Herczegh (Autor) · Springer · Tapa Blanda

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Reseña del libro "synthetic aspects of aminodeoxy sugars of antibiotics (en Inglés)"

The synthetic chemistry of carbohydrates has advanced at a scarcely equalled rate in the last 25 years, due to the great interest of biologically active natural products coritaining sugar moieties. It suffices to note that in the review by J. D. Dutcher appearing in "Advances in Carbohydrate Chemistry" vol. 18, 1963, only the structures of less than ten aminodeoxy sugars were reported. This book deals exclusively with a single class of carbohydrates, namely the aminodeoxy sugars of antibiotics, the most popular of which is probably daunosamine, a compound for which more than 20 different synthetic approaches have been reported in the literature since the publication of its structure in 1964. No compound in the 3-amino-2-deoxY-L-hexose series had been prepared by chemical synthesis when we started our synthetic work in this field in 1972 on the wave of the successful therapeutic applications of adriamycin. The compounds with xylo stereochemistry were unknown even in the more easily accessible D-series. The size of this book documents the rapid development of the field. I wish to add that the improvements of chemical methodology reported in. the volume outspan the specific field and are of importance in the design of synthetic approaches to other carbohydrate structures. These also include compounds involved in chemical interactions of great biological interest, but hitherto un- explained at the molecular level, such as those related with cell recognition, adhesiveness and differentiation.