Name: Spectrophotometric Determination of Clopidogrel Bisulfate (en Inglés)
SKU: 62583516
Price: 1173.38 MXN
Availability: InStock
Author: Harbi Sabrein; Issa Yousry; Salim Alyaa
ISBN: 9783659744921

portada Spectrophotometric Determination of Clopidogrel Bisulfate (en Inglés)

Spectrophotometric Determination of Clopidogrel Bisulfate (en Inglés)

Formato

Libro Físico

Editorial

Lap Lambert Academic Publishing

Autor

Harbi Sabrein; Issa Yousry; Salim Alyaa

Idioma

Inglés

N° páginas

108

Encuadernación

Tapa Blanda

ISBN13

9783659744921

Spectrophotometric Determination of Clopidogrel Bisulfate (en Inglés)

Harbi Sabrein; Issa Yousry; Salim Alyaa (Autor) · Lap Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Spectrophotometric Determination of Clopidogrel Bisulfate (en Inglés)"

Two simple and high sensitive spectrophotometric methods have been developed for the quantitative determination of clopidogrel bisulfate (CLPB), in pure form and in pharmaceutical formulations, through H-point standard addition method (HPSAM) which showed suitable abilities to resolve accurately overlapped absorption spectra of the compounds by simultaneous determination of CLPB in its binary mixture with aspirin (ASP), and the other method is ion-pair formation reactions with some sulphonphthalein, e.g. bromophenol blue (BPB), bromocresol purple (BCP), bromocresol green (BCG), and bromoxylenol blue (BXB). The reaction conditions were studied and optimized. The proposed methods are rapid, accurate, sensitive, selective and cost effective and the methods were successfully applied to the analysis of commercial tablets as Plavix(R), Borgavix(R), and Colsprin(R) (authentic sample). Statistical treatment of the results was performed with regard to accuracy and precision using student's t- and F-tests at 95% confidence level.