Name: Reconstituted Sodium Pump: A Historical Account (en Inglés)
SKU: 60491112
Price: 751.93 MXN
Availability: InStock
Author: Anner, Beatrice Maier
ISBN: 9783389016015

portada Reconstituted Sodium Pump: A Historical Account (en Inglés)

Reconstituted Sodium Pump: A Historical Account (en Inglés)

Formato

Libro Físico

Autor

Beatrice Maier Anner

Editorial

Grin Verlag

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

21x14.8x0.4 cm

Peso

0.09 kg.

ISBN13

9783389016015

Categorías

Química orgánica

Reconstituted Sodium Pump: A Historical Account (en Inglés)

Beatrice Maier Anner (Autor) · Grin Verlag · Tapa Blanda

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Reseña del libro "Reconstituted Sodium Pump: A Historical Account (en Inglés)"

Document from the year 2024 in the subject Chemistry - Bio-chemistry, language: English, abstract: The sodium pump, also called Na, K-ATPase (NKA) is a biomotor inserted in the membrane of all living cells; it extrudes sodium ions from the cell interior and replaces them with potassium ions. This is a fundamental and vital process. Furthermore, the sodium pump is also a receptor for pharmacological and toxicological compounds, such as the heart drug digitoxin and the arrow poison ouabain. Around 1974 it became possible to extract the sodium pump from the cell membrane and insert it into artificial phospholipid vesicles where it worked in the same way as in the cell. Now, the pump could be studied in its pure form on a molecular level. The author has been involved in this pioneering research and tells some fascinating stories concerning the first ultrastructural description of the reconstituted sodium pump in collaboration with specialists at Arhus University in Denmark and at Duke University in the US, and about the use of the reconstituted sodium pump for testing an unknown inhibitory compound in collaboration with Harvard Medical School.