Name: recent developments in the pharmacology of inflammatory mediators: proceedings international symposium, rotterdam, november 76 (en Inglés)
SKU: 25347548
Price: 841.79 MXN
Availability: InStock
Author: Bonta
ISBN: 9783764309145

portada recent developments in the pharmacology of inflammatory mediators: proceedings international symposium, rotterdam, november 76 (en Inglés)

recent developments in the pharmacology of inflammatory mediators: proceedings international symposium, rotterdam, november 76 (en Inglés)

Formato

Libro Físico

Autor

Bonta

Editorial

Birkhauser

Año

1977

Idioma

Inglés

N° páginas

178

Encuadernación

Tapa Blanda

Dimensiones

24.4x17x1 cm

Peso

0.29 kg.

ISBN

3764309148

ISBN13

9783764309145

Categorías

Enciclopedias y obras de consulta
Ciencia: cuestiones generales

recent developments in the pharmacology of inflammatory mediators: proceedings international symposium, rotterdam, november 76 (en Inglés)

Bonta (Autor) · Birkhauser · Tapa Blanda

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Reseña del libro "recent developments in the pharmacology of inflammatory mediators: proceedings international symposium, rotterdam, november 76 (en Inglés)"

In previous studies (1,2) we demonstrated the occurrence of a foetal protein after injury in the rat. This protein, behaving as an acute phase protein, proved to be already known as slow a2 glo- bulin (3), or reproduction associated protein (4). Furthermore it is identical to aM foetoprotein (also known as a2FP or aMFP (5) ). This protein is quite different to the well-known a-foetoprotein (aFP), occurring in man and other species during liver carcinoge- nesis and some other tumours. aMfoetoprotein (aMFP) is a glycoprotein with a mol.w. of 800.000. It is produced in the liver (6,2) and in the normal adult rat the plasma concentrations are rather low, about 0 - 40 g/ml. During fetal development the plasma level in the fetus is much higher (about 6000 g/ml), diminishing rapidly after birth to adult levels. But after injury (laparotomy, deep incision, partial hepatectomy followed by regeneration, BaS04 or CdS04 intraperitoneally), plasma levels increase fastly, reaching peak values of 1000 - 8000 g/ml after 24 - 48 hrs, declining thereafter gradually. Also very small lesions, as orbital punction, venasection, cannulations, small infections and so on, cause moderate rises of plasma levels up to 80 - 120 g/ml. During fetal stage the inflammatory reaction often lacks some of its characteristic features: oedema and infiltration of leucocytes are often rather scanty (7). Also is known that in exudates proteins occur, inhibiting experimen- tal inflammations (8,9).