Name: Parkinson's Disease: Insights Into Pathogenesis and Symptomatology: Parkinson's Disease: Understanding Pathogenesis, Symptoms, and Challenges (en Inglés)
SKU: 63814046
Price: 993.72 MXN
Availability: InStock
Author: Mona El-Banna
ISBN: 9783639714111

portada Parkinson's Disease: Insights Into Pathogenesis and Symptomatology: Parkinson's Disease: Understanding Pathogenesis, Symptoms, and Challenges (en Inglés)

Parkinson's Disease: Insights Into Pathogenesis and Symptomatology: Parkinson's Disease: Understanding Pathogenesis, Symptoms, and Challenges (en Inglés)

Formato

Libro Físico

Editorial

Scholars' Press

Autor

Mona El-Banna

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

ISBN13

9783639714111

Parkinson's Disease: Insights Into Pathogenesis and Symptomatology: Parkinson's Disease: Understanding Pathogenesis, Symptoms, and Challenges (en Inglés)

Mona El-Banna (Autor) · Scholars' Press · Tapa Blanda

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Reseña del libro "Parkinson's Disease: Insights Into Pathogenesis and Symptomatology: Parkinson's Disease: Understanding Pathogenesis, Symptoms, and Challenges (en Inglés)"

Parkinson's disease (PD) is a common neurodegenerative disorder affecting over 10 million people worldwide, with prevalence rising with age. It is characterized by motor symptoms like bradykinesia and rigidity, and non-motor symptoms driven by dopaminergic neuron loss in the substantia nigra pars compacta (SNpc). Key pathological features include alpha-synuclein aggregation into Lewy bodies, mitochondrial dysfunction, oxidative stress, and neuroinflammation.As PD progresses, dopamine depletion worsens, leading to advanced motor complications and non-motor impairments. Current treatments alleviate symptoms but do not prevent neurodegeneration. Understanding the mechanisms of alpha-synuclein aggregation, mitochondrial dysfunction, and neuroinflammation is essential for developing effective disease-modifying therapies.