Name: Histologic Examination of Host-Parasite Interactions Fundulus Grandis: Examining the Cellular Immune Response in the Gulf Killifish to Nematode Parasites Found Within the Mesenteries (en Inglés)
SKU: 62591918
Price: 4993.31 MXN
Availability: InStock
Author: Marlee Marsh
ISBN: 9783639766592

portada Histologic Examination of Host-Parasite Interactions Fundulus Grandis: Examining the Cellular Immune Response in the Gulf Killifish to Nematode Parasites Found Within the Mesenteries (en Inglés)

Histologic Examination of Host-Parasite Interactions Fundulus Grandis: Examining the Cellular Immune Response in the Gulf Killifish to Nematode Parasites Found Within the Mesenteries (en Inglés)

Formato

Libro Físico

Editorial

Scholars' Press

Autor

Marlee Marsh

Idioma

Inglés

N° páginas

120

Encuadernación

Tapa Blanda

ISBN13

9783639766592

Histologic Examination of Host-Parasite Interactions Fundulus Grandis: Examining the Cellular Immune Response in the Gulf Killifish to Nematode Parasites Found Within the Mesenteries (en Inglés)

Marlee Marsh (Autor) · Scholars' Press · Tapa Blanda

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Reseña del libro "Histologic Examination of Host-Parasite Interactions Fundulus Grandis: Examining the Cellular Immune Response in the Gulf Killifish to Nematode Parasites Found Within the Mesenteries (en Inglés)"

Little is known about the immunobiology of fish responses to parasitic infections. The aim of this study was to describe a model for fish-nematode interactions on the immunological front, and to develop new reagents for the study of this model. Gulf killifish, Fundulus grandis, were collected over two seasons from MS, USA, and examined for endoparasites, particularly the larval nematode Eustrongylides ignotus. A baseline study was preformed to determine the prevalence, intensity, and histologic features of E. ignotus infection in F. grandis. In addition, two monoclonal antibodies, (mAb) M24-2 and 2C11, were characterized for their use in this project, as well as for general applications in fish immunobiology. mAb M24-2 was developed and found to recognize a 14.5 kD protein in serum from all fish tested, and recognizes hen egg lysozyme (HEL). mAb 2C11 was developed and determined to recognize a 17 kD protein found in fish cell lysates, but in not plasma. It was determined that mAb 2C11 recognizes granule content of a small population of highly granulated cells, most likely eosinophilic granular cells (EGCs). Like mAb M24-2, mAb 2C11 was found to be cross reactive in other fish.