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portada Enabling Precision Medicine. The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop
Formato
Libro Físico
Editorial
Autor
Año
2017
N° páginas
144
Encuadernación
Tapa Blanda
Dimensiones
22.9x15.2x2.5 cm
ISBN13
9780309462631

Enabling Precision Medicine. The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop

Board On Health Sciences Policy;Theresa Wizemann;Siobhan Addie;Sarah H. Beachy;Morgan L. Boname;Amanda Wagner Gee;Roundtable On Genomics And Precision Health;Health And Medicine Division;Engineering, And Medicine National Academies Of Sciences;Development (Autor) · National Academies Press · Tapa Blanda

Enabling Precision Medicine. The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop - Board on Health Sciences Policy;Theresa Wizemann;Siobhan Addie;Sarah H. Beachy;Morgan L. Boname;Amanda Wagner Gee;Roundtable on Genomics and Precision Health;Health and Medicine Division;Engineering, and Medicine National Academies of Sciences;Development

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Reseña del libro "Enabling Precision Medicine. The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop"

Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a potentially disruptive change that could improve patient outcomes, reduce costs associated with drug development, and further realize the goals of precision medicine. On March 8, 2017, the Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development. Participants examined successes, challenges, and possible best practices for effectively using genetic information in the design and implementation of clinical trials to support the development of precision medicines, including exploring the potential advantages and disadvantages of such trials across a variety of disease areas. This publication summarizes the presentations and discussions from the workshop. Table of ContentsFront Matter1 Introduction2 Overarching Considerations for Implementing Successful Genetics-Enabled Drug Development3 Case Studies in Precision Drug Development4 Integrating Genetics into the Drug Development Pathway for Complex Diseases5 Finding Innovative Ways to Integrate Genetic Research into the Drug Development Process6 Reflecting Back and Looking Forward: Key Themes and Potential Next Steps in Genetics-Enabled Drug DevelopmentAppendix A: ReferencesAppendix B: Statement of Task and Workshop AgendaAppendix C: Speaker Biographical SketchesAppendix D: Registered Attendees

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