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Efficacy of Aloin Mediated Phytogenic Nanosilver in Murine Mastitis (en Inglés)
Thota Venkata, Chaitanya Kumar; P, Eswara Prasad; K, Padmaja (Autor)
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LAP Lambert Academic Publishing
· Tapa Blanda
Efficacy of Aloin Mediated Phytogenic Nanosilver in Murine Mastitis (en Inglés) - Thota Venkata, Chaitanya Kumar; P, Eswara Prasad; K, Padmaja
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Reseña del libro "Efficacy of Aloin Mediated Phytogenic Nanosilver in Murine Mastitis (en Inglés)"
An experimental study was conducted to evaluate the efficacy of aloin mediated phytogenic nanosilver particles in experimental murine mastitis. The nanoparticles were synthesized and the synthesized nanoparticles were characterized using UV-visible spectrophotometer, Scanning electron microscope (SEM), DLS (Dynamic light scaterring) Technique and FT-IR analysis and were also evaluated for antimicrobial activity and cytotoxic effects.A total of 40 female mice between 10-15 days of lactation were utilized for the study. The animals were divided into five groups of eight animals each. Group I served as lactating control, groups II to V were inoculated with 20 l of 24h broth culture of S.aureus containing 4.0 x 104 cfu/quarter under ketamine anaesthesia using 33g blunt hamilton needle. After 6h post inoculation, groups III and IV received 20 l of Aloin nano silver (ANS) through intramammary and intra peritoneal routes respectively. Group V received antibiotic Cefepime at a dose rate of 1mg/kg body weight through intra peritoneal route. After 18 h post treatment, serum C reactive protein (CRP) levels, weights of mammary glands, mammary bacterial loads, levels of TBARS, GSH, SOD.