Name: Development of Fenoprofen Calcium Tablets for Colon Targeting (en Inglés)
SKU: 66202892
Price: 883.33 MXN
Availability: InStock
Author: Shinde, Anilkumar; Gaikwad, Dinanath; More, Harinath
ISBN: 9786206739494

portada Development of Fenoprofen Calcium Tablets for Colon Targeting (en Inglés)

Development of Fenoprofen Calcium Tablets for Colon Targeting (en Inglés)

Formato

Libro Físico

Editorial

LAP Lambert Academic Publishing

Autor

Shinde, Anilkumar; Gaikwad, Dinanath; More, Harinath

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x0.3 cm

ISBN13

9786206739494

Development of Fenoprofen Calcium Tablets for Colon Targeting (en Inglés)

Shinde, Anilkumar; Gaikwad, Dinanath; More, Harinath (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Development of Fenoprofen Calcium Tablets for Colon Targeting (en Inglés)"

Objective: The objective of the present investigation was to development of enteric coated tablet of fenoprofen calcium. Methods: The 32factorial design was used to preparation of compression‐coated with a mixture of time dependent hydrophilic swellable polymer hydropropylcellulose (HPC), time released polymer Ethyl cellulose (EC) and pH responsive soluble polymer Instacoat EN Super II. The developed formulations were characterized for angle of repose, density, carr's index of powder mixture and thickness, diameter, hardness, friability, weight variation, uniformity content, in vitro disintegration, dissolution study. Results: The results showed that disintegration time and dissolution study of inner core tablet found to be in the range of 7.15 to 13.34 min and 95.92 0.011% at 30 min. The press coat tablets at optimum concentrations of hydroxy propyl cellulose (200 mg) and ethyl cellulose N-22 (200 mg) showed the % drug release 83.53 0.014% at 12 hr. % cumulative drug release of enteric coated tablet of optimized batch FT9 showed 76.08 0.045 at 12h, it indicated that drug release at sustained manner.