Name: A Pneumococcal Protein Glycocapture Approach
SKU: 53043528
Price: 737.44 MXN
Availability: InStock
Author: Alfonso Olaya Abril
ISBN: 9786202101806

portada A Pneumococcal Protein Glycocapture Approach

A Pneumococcal Protein Glycocapture Approach

Formato

Libro Físico

Autor

Alfonso Olaya Abril

Encuadernación

Tapa Blanda

ISBN13

9786202101806

Categorías

Bioquímica

A Pneumococcal Protein Glycocapture Approach

Alfonso Olaya Abril (Autor) · · Tapa Blanda

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Reseña del libro "A Pneumococcal Protein Glycocapture Approach"

Emergence of pneumococcal multi-drug resistant clinical isolates prompts the need for a more effective vaccine for the prevention of disease. For this purpose, glycoproteins could be excellent candidates because of their implication in a number of biological processes, such as cell-to-cell recognition and the host immune response. In this study, methods widely used to capture potential surface proteins independently of their glycosylation status were carried out, and Concanavalin A (ConA) and Hydrazide subproteomes were obtained from different pneumococcal subcellular fractions (membrane, lysate, secretome and membrane-derived vesicles (MVs)) followed by protein LC-MS/MS analysis. In addition, a 2DE multilectinblotting (2DEMLB) analysis, using ConA, WGA, UEA, BC-1 and PNA lectins, was performed. Alfonso Olaya Abril*, Lidia Gómez Gascón, Irene Jiménez Munguía, Michael J. McConnell, Meritxell García Quintanilla, Ignacio Obando Santaella, Manuel José Rodríguez Ortega.