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Astrogliosis and Channel Function
John V. Zimmerman
(Autor)
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Mujeeb Publishers
· Tapa Blanda
Astrogliosis and Channel Function - V. Zimmerman, John
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Reseña del libro "Astrogliosis and Channel Function"
Astrogliosis is a hallmark of central nervous system (CNS) neuroinflammatory disorders such as multiple sclerosis (MS). Astrocytes can playboth beneficial and detrimental roles in response to neuroinflammation, thus a detailed understanding of the underlying molecular mechanisms governingastrogliosis might facilitate the development of therapeutic targets. While astrocytes do not express voltage-gated sodium channel (VGSC) Nav1.5 innonpathological human brain, they exhibit robust upregulation of Navi .5 within acute and chronic MS lesions
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