Section I. Compartments and Pathways 1. Overview of Intracellular Compartments and Trafficking Pathways Andrei A. Tokarev, Aixa Alfonso and Nava Segev 2. How We Study Protein Transport Mary L. Preuss, Peggy Weidman and Erik Nielsen 3. The Golgi Apparatus Zhaolin Hua and Todd R. Graham 4. The Endocytic Pathway Elizabeth Conibear and Yuen Yi C. Tam 5. Regulated Secretion Naveen Nagarajan, Kenneth L. Custer and Sandra Bajjalieh Section II. Mechanisms 6. Overview of Protein Trafficking Mechanisms Giancarlo Costaguta and Gregory S. Payne 7. Entry into the Endoplasmic Reticulum: Protein Translocation, Folding and Quality Control Sheara W. Fewell and Jeffrey L. Brodsky 8. COP-Mediated Vesicle Transport Silvere Pagant and Elizabeth Miller 9. Clathrin-Mediated Endocytosis Peter S. McPherson, Brigitte Ritter and Beverly Wendland 10. Biogenesis of Dense-Core Secretory Granules Grant R. Bowman, Andrew T. Cowan and Aaron P. Turkewitz 11. Lipid-Dependent Membrane Remodelling in Protein Trafficking Priya P. Chandra and Nicholas T. Ktistakis 12. Carrier Motility Marcin J. Wozniak and Victoria J. Allan 13. Tethering Factors Vladimir Lupashin and Elizabeth Sztul 14. Intracellular Membrane Fusion Dalu Xu and Jesse C. Hay Section III. Regulation and Coordination with Other Cellular Processes 15. Regulation and Coordination of Intracellular Trafficking: An Overview Julie Donaldson and Nava Segev 16. Regulation of Protein Trafficking by GTP-Binding Proteins Michel Franco, Philippe Chavrier and Florence Niedergang 17. Posttranslational Control of Protein Trafficking in the Post-Golgi Secretory and Endocytic Pathway &nb