The interpretation of the natal charts (that is to say, of the drawing representing the celestial positions of our solar system at the moment of one's birth) is probably the milestone of all Astrological Knowledge. It is the point of confluence of the science in which - in a mass of fascinating synergies - disciplines such as astronomy, astrology, mythology, psychology, and a hundred other forms of Knowledge converge that together form what should be understood for Holistic Knowledge. The master of astrology, enriched by multi-decennial experiences, has the gift of synthesis, the ability of photographing in a moment all the Microcosm-Macrocosm that encloses past, present and future of every human being through the glyphs of planets, the Houses, and the angular aspects among the elements of the chart. This volume represents the University of Astrology. It is not coincidental that its Author, who is one of the most accomplished astrologer of the world, sought to engage in the writing of this short treatise, about the same time of the turning point of his own professional jubilee (defined by the number of works that he has published so far). With the simplicity that distinguishes him, on this occasion too, Ciro Discepolo has been able to present to both neophytes and the more experienced readers the most difficult concepts in a direct, simple, immediately usable way, revealing previously unpublished details, new knowledge that he has meditated for long before writing about it, and even small secrets of what must necessarily be called the Interpretative Art of Astrology. As is his custom, the Author offers over fifty examples to support the explained theories. They consist mainly in the natal charts of celebrities, completely revised compared to past editions, or interpreted now for the first time for the delight of his students.