The symposium "Star Clusters in the Era of Large Surveys" was held in Lisbon on Sep 9-10 during the JENAM 2010. It served as a platform for discussing what and how recent, on-going and planned large-area ground-based and space-based surveys can contribute to producing a major leap in this research field, which has a strong European history.Scientific topics addressed included: cluster searches, clustered vs. isolated star formation, large-scale star formation, enrichment of the field population, structure, populations and evolution of the Milky Way, cluster dynamics (internal and within the Milky Way), variability of stars in clusters (from time-resolved surveys), analysis techniques for large samples and archiving.This proceedings book provides a snapshot of the ongoing discussion on the role of large surveys in star cluster research, and serves as a reference volume for the state-of-the art in the field.